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| The Effects of External Compression on Venous Blood Flow and Tissue Deformation in the Lower Leg |
| Source: Dai G, Gertler J, Kamm RD: Journal of Biomechanical Engineering 121: 1-8, 1999 |
| Summary: Finite element analysis was used to examine the stress distribution within the tissues, and the corresponding venous blood flow and intravascular shear stress with different external compression modalities. Circumferentially symmetric (C) compression was compared to asymmetrical (A) compression, with axial distribution being either uniform or graded sequential. "The results show that A compression produces greater vessel collapse and generates larger blood flow velocities and shear stresses than C compression." Elevated levels of shear stress can influence the release of fibrinolytic agents, demonstrating that fluid dynamic effects might modulate fibrinolysis. |