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| Effect of Optimization of Hemodynamics on Fibrinolytic Activity and Antithrombotic Efficacy of External Pneumatic Calf Compression |
| Source: Salzman EW, McManama GP, Shapiro AH, et al. Ann Surgery 206(5): 636-641, 1987 |
| Summary: A comparison of the hemodynamics of uniform compression vs. graded sequential compression was conducted using a custom-designed cuff to meet optimal parameters for graded sequential compression. They found that "a system for external pneumatic compression in which the pressure was applied in a graded fashion, milking the blood from ankle to knee, was more effective hemodynamically, and in the clinical trial it proved to be more effective in enhancement of fibrinolytic activity than uniform compression…". |